UMass Boston

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Kimberly Hamad

Department:
Engineering
Title:
Graduate Program Director/Professor
Location:
McCormack Hall Floor 03
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Area of Expertise

Nanotechnology, Nanobiotechnology, Nanomaterials, Rapid Diagnostics

Degrees

PhD, University of California at Berkeley

SB, Massachusetts Institute of Technology

Professional Publications & Contributions
  • Gomez-Marquez J, Hamad-Schifferli K. Distributed Biological Foundries for Global Health. Advanced Healthcare Materials (2019), 1900184.
  • Russo L, Sánchez-Purrà M, Rodriguez-Quijada C, Leonardo BM, Puntes V, Hamad-Schifferli K. Detection of myxovirus resistance protein A (MxA) in paper-based immunoassays with surface enhanced Raman spectroscopy with AuAg nanoshells. Nanoscale (2019) 11 (22), 10819-10827.
  • Wick S, Walsh III DI, Bobrow J, Hamad-Schifferli K, Kong DS, Thorsen T, Mroszczyk K, Carr PA. PERSIA for Direct Measurement of Transcription, Translation, and Enzyme Activity in Cell-Free Systems. ACS Synthetic Biology (2019) 8 (15) 1010-1025.
  • Rodriguez-Quijada C, de Puig H, Sánchez-Purrà M, Yelleswarapu C, Evans JJ, Celli JP, Hamad-Schifferli K. Protease degradation of protein coronas and its impact on cancer cells and drug payload release. ACS Applied Materials and Interfaces (2019) 11 (16) 14588–14596.
  • Hristov DR, Rodriguez-Quijada C, Gomez-Marquez J, Hamad-Schifferli K*. Designing Paper-Based Immunoassays for Biomedical Applications. Sensors (2019), 19 (3) 554.
  • Rodriguez-Quijada C, Hamad-Schifferli K.* “Applications of Photo-triggered Theranostic Nanomaterials,” in the "Handbook of Nanomaterials for Cancer Theranostics: from the Chemical to the Biological Realm." Elsevier, Advanced Nanomaterials book series, edited Ashutosh Tiwari, 2018.
  • Sánchez-Purrà M, Roig-Solvas B, Rodriguez-Quijada C, Leonardo BM, Hamad-Schifferli K.* Reporter selection for Nanotags in Multiplexed Surface Enhanced Raman Spectroscopy Assays. ACS Omega (2018), 3 (9) 10733–10742.
  • Phillips E, Young AK, Albarran A, Butler J, Lujan K, Hamad-Schifferli K, Gomez-Marquez J. Ampli: A Construction Set for Paperfluidic Systems. Advanced Healthcare Materials (2018), 1800104.
  • Rodriguez-Quijada C,† Sánchez-Purrà M,de Puig G, Hamad-Schifferli K.* Physical Properties of Biomolecules at the Nanomaterial Interface. Journal of Physical Chemistry B (2018), 122 (11) 2827-2840.
  • Sánchez-Purrà M, Roig-Solvas B, Versiani A, Rodríguez-Quijada C, de Puig H, Bosch I, Gehrke L, Hamad-Schifferli K.* Design of SERS nanotags for multiplexed lateral flow immunoassays. Molecular Systems Design & Engineering (2017), 2, 401-409.
  • Bosch I,* de Puig H,* Hiley M, Carré-Camps M, Perdomo-Celis F, Narváez CF, Salgado DM, Senthoor D, O’Grady M, Phillips E, Durbin A, Fandos D, Miyazaki H, Yen C-W, Gélvez-Ramírez M, Warke RV, Ribeiro LS, Teixeira MM, Almeida RP, Muñóz-Medina JE, Ludert J, Nogueira ML, Colombo TE, Terzian ABC, Bozza PT, Calheiros AS, Vieira YR, Barbosa-Lima G, Vizzoni A, Cerbino-Neto J, Bozza FA, Souza TML, Trugilho MRO, de Filippis AMB, de Sequeira PC, Marques ETA, Magalhaes T, Díaz FJ, Restrepo BN, Marín K, Mattar S, Olson D, Asturias EJ, Lucera M, Singla M, Medigeshi GR, de Bosch N, Tam J, Gómez-Márquez J, Clavet C, Villar L, Hamad-Schifferli K,† Gehrke L.† Rapid antigen tests for dengue virus serotypes and Zika virus in patient serum. Science Translational Medicine (2017), 9, eaan1589.
  • de Puig H, Bosch I, Gehrke L, Hamad-Schifferli K.* Challenges of the nano-bio interface lateral flow and dipstick immunoassays. Trends in Biotechnology (2017), 35 (12), 1169-1180.
  • Gao J, Sánchez-Purrà M, Huang H, Wang S, Chen Y, Yu X, Luo Q, Hamad-Schifferli K,* Liu S.* Synthesis of different-sized gold nanostars for Raman bioimaging and photothermal therapy in cancer nanotheranostics. Science China Chemistry (2017), 60, 1219–1229.
  • de Puig H, Bosch I, Carré-Camps M, Hamad-Schifferli K. Effect of the protein corona on antibody-antigen binding in nanoparticle sandwich immunoassays. Bioconjugate Chemistry (2017), 28, 230-238.
  • Tam JO, de Puig H, Yen C, Bosch I, Gomez-Marquez J, Clavet C, Hamad-Schifferli K, Gehrke L, A Comparison of Nanoparticle-Antibody Conjugation Strategies in Sandwich Immunoassays. Journal of Immunoassay and Immunochemistry (2017), 1-23.
  • Yen C-W, de Puig H, Tam J, Gómez-Márquez J, Bosch I, Hamad-Schifferli K, and Gehrke L. Multicolored Silver Nanoparticles for Multiplexed Disease Diagnostics: Distinguishing Dengue, Yellow Fever, and Ebola Viruses. Lab on a Chip (2015) 15, 1638-41.
  • Liberman V, Hamad-Schifferli K, Thorsen TA, Wick ST, and Carr PA. In-Situ Microfluidic Sers Assay for Monitoring Enzymatic Breakdown of Organophosphates. Nanoscale (2015) 7, 11013-110023.
  • Hamad-Schifferli K. Exploiting the Novel Properties of Protein Coronas: Emerging Applications in Nanomedicine. Nanomedicine (2015) 10, 1663-74.
  • de Puig H, Tam JO, Yen C-W, Gehrke L, and Hamad-Schifferli K. The Extinction Coefficient of Gold Nanostars. Journal of Physical Chemistry C (2015) 119, 17408-15.
  • Kah JCY, Grabinski CM, Untener E, Garrett C, Chen J, Zhu D, Hussain SM, and Hamad-Schifferli K. Protein Coronas on Gold Nanorods Passivated with Amphiphilic Ligands Affect Cytotoxicity and Cellular Response to Penicillin/Streptomycin. ACS Nano (2014) 85 (5), 4608-20.
  • Hamad-Schifferli K. "Stability of Dispersions and Interactions in Nanostructured Fluids " In Colloidal Foundations of Nanoscience, edited by Debora Berti and Gerardo Palazzo. Amsterdam: Elsevier, 2014.
  • Ciaurriz P, Bravo E, and Hamad-Schifferli K. Effect of Architecture on the Activity of Glucose Oxidase/Horseradish Peroxidase/Carbon Nanoparticle Conjugates. Journal of Colloid and Interface Science (2014) 414, 73-81.
  • Suntivich J, Xu Z, Carlton CE, Kim J, Han B, Lee SW, Bonnet N, Marzari N, Allard LF, Gasteiger HA, Hamad-Schifferli K, and Shao-Horn Y. Surface Composition Tuning of Au-Pt Bimetallic Nanoparticles for Enhanced Carbon Monoxide and Methanol Electro-Oxidation. Journal of the American Chemical Society (2013) 135 (21), 7985-91.
  • Maiolo D, Federici S, Ravelli L, Depero LE, Hamad-Schifferli K, and Bergese P. Nanomechanics of Surface DNA Switches Probed by Captive Contact Angle. Journal of Colloid and Interface Science (2013) 402, 334-39.
  • Hamad-Schifferli K. How Can We Exploit the Protein Corona? Nanomedicine (2013) 8 (1), 1-3.
  • de Puig Guixé H, Cifuentes Rius A, Flemister D, Baxamusa SH, and Hamad-Schifferli K. Selective Light-Triggered Release of DNA from Gold Nanorods Switches Blood Clotting on and Off. PLOS ONE (2013) 8 (7), e68511.
  • Cifuentes-Rius A, de Puig Guixé H, Kah JCY, Borros S, and Hamad-Schifferli K. Optimizing the Properties of the Protein Corona Surrounding Nanoparticles for Payload Release. ACS Nano (2013) 7 (11), 10066-74.
  • Bergese P, and Hamad-Schifferli K, eds. Nanomaterial Interfaces in Biology: Methods and Protocols. Edited by John M. Walker. Vol. 1025, Methods in Molecular Biology. New York: Springer Science + Business Media, 2013.
  • Xu Z, Lai E, Shao-Horn Y, and Hamad-Schifferli K. Compositional Dependence of the Stability of Aucu Alloy Nanoparticles. Chemical Communications (2012) 48 (45), 5626-28.
  • Tellechea E, Wilson K, Bravo E, and Hamad-Schifferli K. Engineering the Interface between Glucose Oxidase and Nanoparticles. Langmuir (2012) 28 (11), 5190-200.
  • Kah JCY, Chen J, Zubieta A, and Hamad-Schifferli K. Exploiting the Protein Corona around Gold Nanorods for Loading and Triggered Release ACS Nano (2012) 6 (8), 6730-40.
  • Kah JCY, Zubieta A, Saavedra RA, and Hamad-Schifferli K. Stability of Gold Nanorods Passivated with Amphiphilic Ligands. Langmuir (2012) 28 (24), 8834-44.
  • Grabinski C, Schaeublin N, Wijaya A, D’Couto H, Baxamusa SH, Hamad-Schifferli K, and Hussain SM. Effect of Gold Nanorod Surface Chemistry on Cellular Response. ACS Nano (2011) 5 (4), 2870-79.
  • de Puig H, Federici S, Baxamusa SH, Bergese P, and Hamad-Schifferli K. Quantifying the Nanomachinery of the Nanoparticle-Biomolecule Interface. Small (2011) 7 (17), 2477-84.
  • Xu Z, Xu Z, Carlton CE, Allard LF, Shao-Horn Y, and Hamad-Schifferli K. Direct Colloidal Route for Pt-Covered Aupt Bimetallic Nanoparticles. Journal of Physical Chemistry Letters (2010) 1 (17), 2514-18.
  • Park S, Sinha N, and Hamad-Schifferli K. Effective Size and Zeta Potential of Nanorods by Ferguson Analysis. Langmuir (2010) 26 (16), 13071-75.
  • Park S, and Hamad-Schifferli K. Nanoscale Interfaces to Biology. Current Opinion in Chemical Biology (2010) 14 (5), 616–22.
  • Park, S, Hamad-Schifferli K. Enhancement of in Vitro Translation Using Gold Nanoparticle-DNA Conjugates. ACS Nano (2010) 4 (5), 2555-60.
  • Lu Y-C, Xu Z, Gasteiger HA, Chen S, Hamad-Schifferli K, and Shao-Horn Y. Platinum-Gold Nanoparticles: A Highly Active Bifunctional Electrocatalyst for Rechargeable Lithium-Air Batteries. Journal of the American Chemical Society (2010) 32 (135), 12170-71.
  • Federici S, Oliviero G, Hamad-Schifferli K, and Bergese P. Protein Thin Film Machines. Nanoscale (2010) 2, 2570-74.
  • Alper JD, and Hamad-Schifferli K. Effect of Ligands on Thermal Dissipation from Gold Nanorods. Langmuir (2010) 26 (6), 3786–89.
  • Wijaya A, Schaffer SB, Pallares IG, and Hamad-Schifferli K. Selective Release of Multiple DNA Oligonucleotides from Gold Nanorods ACS Nano (2009) 3 (1), 80-86.
  • Aubin-Tam M-E, Hwang W, and Hamad-Schifferli K. Site-Directed Nanoparticle Labeling of Cytochrome C. Proceedings of the National Academy of Sciences (2009) 106 (11), 4095-100.
  • Alper JD, Crespo M, and Hamad-Schifferli K. Release Mechanism of Octadecyl Rhodamine B Chloride from Au Nanorods by Ultrafast Laser Pulses. Journal of Physical Chemistry C (2009) 113 (15), 5967-73.
  • Wijaya A, and Hamad-Schifferli K. Ligand Customization and DNA Functionalization of Gold Nanorods Via Round-Trip Phase Transfer Ligand Exchange. Langmuir (2008) 24 (18), 9966-69.
  • Schmidt AJ, Alper JD, Chiesa M, Chen G, Das SK, and Hamad-Schifferli K. Probing the Gold Nanorod-Ligand-Solvent Interface by Plasmonic Absorption and Thermal Decay. Journal of Physical Chemistry C (2008) 112 (35), 13320-23.
  • Park S, and Hamad-Schifferli K. Evaluation of Hydrodynamic Size and Zeta-Potential of Surface-Modified Au Nanoparticle-DNA Conjugates Via Ferguson Analysis. Journal of Physical Chemistry C (2008) 112 (20), 7611-16.
  • Brown KA, Park S, and Hamad-Schifferli K. Nucleotide-Surface Interactions in DNA Modified Au-Nanoparticle Conjugates: Sequence Effects on Reactivity and Hybridization. Journal of Physical Chemistry C (2008) 112 (20), 7517-21.
  • Aubin-Tam M-E, Zhou H, and Hamad-Schifferli K. Structure of Cytochrome C at the Interface with Magnetic Cofe2o4 Nanoparticles. Soft Matter (2008) 4, 554-59.
  • Aubin-Tam M-E, and Hamad-Schifferli K. Structure and Function of Nanoparticle-Protein Conjugates. Biomedical Materials (2008) 3, 034001.
  • Wijaya A, and Hamad-Schifferli K. High Density Encapsulation of Fe3o4 Nanoparticles in Lipid Vesicles. Langmuir (2007) 23 (19), 9546-50.
  • Wijaya A, Brown KA, Alper JD, and Hamad-Schifferli K. Magnetic Field Heating Study of Fe Doped Au Nanoparticles. Journal of Magnetism and Magnetic Materials (2007) 309 (1), 15-19.
  • Griffith LG, and Hamad-Schifferli K. "Teaching the Second Law: Statistical Mechanics of Biomolecular Systems." In Proceedings of the Keenan Symposium: Meeting the Entropy Challenge, edited by Gian Paolo Beretta, Ahmed Ghoniem and George Hatsopoulos. Cambridge: AIP, 2007.
  • Aubin-Tam M-E, and Hamad-Schifferli K. Gold Nanoparticle-Cytochrome C Complexes: The Effect of Nanoparticle Ligand Charge on Protein Structure. Langmuir (2005) 21 (26), 12080-84.
  • Aubin M-E, Morales DG, and Hamad-Schifferli K. Labeling Ribonuclease S with a 3nm Au Nanoparticle by Two-Step Assembly. Nano Letters (2005) 5 (3), 519-22.
  • Park S, Brown KA, and Hamad-Schifferli K. Changes in Oligonucleotide Conformation on Nanoparticle Surfaces by Modification with Mercaptohexanol. Nano Letters (2004) 4 (10), 1925-29.